The development of the vertebral column

– Which germ layer vertebral column derives from?

– Overview of: gastrulation to paraxial mesoderm, paraxial mesoderm undergoes segmentation to form somites (somitogenesis), differentiation of somites, then congenital scoliosis and spondocostal dysostosis.

What defines paraxial from axial, lateral mesoderm?

– Also maybe some fate mapping that shows vertebral column is from paraxial mesoderm.

– Somites form rostral to caudal, they have anterior/posterior polarity

2) Signalling in segmentation.

3) Differentiation of somites.

Brief Summary.