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This proposal shall include
Hypothesis and 3 Objectives:
1. Profiling/Deep Sequencing of miRNAs for their expressions in colorectal cancerous tissues;
2. Validation of miRNA expressions in colorectal cancerous tissues and their correlations with circulating miRNAs;
3. Identification of key miRNA target genes that control the development of colorectal cancers.
Approaches and Methodologies:
Please draw some schematic figures to indicate the possible mechanisms of miRNA and colon cancer in Predicted Results or Discussion.
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