- Begin with a protozoan (you pick the specificÂ type) and Â specify what it uses it’s ATP for (in other words, what metabolic process uses the ATP as fuel. 2. Imagine a single point mutation in this use of ATP that changes how/how much ATP is used for this metabolic process. Specify the changes! 3. Explain how this mutation is passed on from cell to cell (remember: most mutations are not large so let’s assume it is not a fatal one). What processes dictate the passing of the mutation 4. Predict (over time) how the mutation will accumulate (or not) in the population of cells.